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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED13L
All Species:
31.21
Human Site:
S2159
Identified Species:
57.22
UniProt:
Q71F56
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q71F56
NP_056150.1
2210
242602
S2159
R
V
P
H
P
L
D
S
K
T
T
S
D
V
L
Chimpanzee
Pan troglodytes
XP_001138050
2188
240763
S2137
K
H
S
H
P
L
D
S
N
Q
T
S
D
V
L
Rhesus Macaque
Macaca mulatta
XP_001112106
2210
242628
S2159
R
V
P
H
P
L
D
S
K
T
T
S
D
V
L
Dog
Lupus familis
XP_534693
2280
250152
S2229
R
V
P
H
P
L
D
S
K
T
T
S
D
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6JPI3
2207
241740
S2156
R
A
P
H
P
L
D
S
K
T
T
S
D
V
L
Rat
Rattus norvegicus
NP_001101807
1374
149708
K1324
A
P
H
P
L
D
S
K
T
T
S
D
V
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509907
2170
238695
S2119
K
H
S
H
P
L
D
S
N
Q
T
S
D
V
L
Chicken
Gallus gallus
XP_415317
2195
241321
S2144
R
V
P
H
P
L
D
S
K
T
T
S
D
V
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2VCZ5
2102
230974
S2051
K
H
S
H
P
L
D
S
S
H
T
S
D
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KTX8
2618
280005
P2564
H
Q
S
G
N
D
H
P
L
D
S
N
L
T
A
Honey Bee
Apis mellifera
XP_393643
1982
216109
Q1932
T
A
H
P
L
D
S
Q
Y
T
T
D
V
L
R
Nematode Worm
Caenorhab. elegans
Q93442
2862
325119
S2810
K
D
A
H
P
L
E
S
R
Q
T
E
E
V
L
Sea Urchin
Strong. purpuratus
XP_001203054
1127
123639
D1077
H
S
H
P
L
D
S
D
R
T
P
E
V
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.7
99.2
93.3
N.A.
92.4
57.7
N.A.
53.5
86.4
N.A.
50.2
N.A.
24.8
33.9
21.2
25.6
Protein Similarity:
100
69.3
99.6
94.7
N.A.
95.7
59.9
N.A.
69.7
92.5
N.A.
66.4
N.A.
41.5
50.5
38.5
35.1
P-Site Identity:
100
66.6
100
100
N.A.
93.3
6.6
N.A.
66.6
100
N.A.
66.6
N.A.
0
13.3
46.6
6.6
P-Site Similarity:
100
73.3
100
100
N.A.
93.3
20
N.A.
73.3
100
N.A.
73.3
N.A.
13.3
20
73.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
8
0
0
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
31
62
8
0
8
0
16
62
0
0
% D
% Glu:
0
0
0
0
0
0
8
0
0
0
0
16
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
16
24
24
70
0
0
8
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
31
0
0
0
0
0
0
8
39
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
24
70
0
0
8
0
0
0
8
24
70
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
16
0
0
8
0
0
0
% N
% Pro:
0
8
39
24
70
0
0
8
0
0
8
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
8
0
24
0
0
0
0
0
% Q
% Arg:
39
0
0
0
0
0
0
0
16
0
0
0
0
0
24
% R
% Ser:
0
8
31
0
0
0
24
70
8
0
16
62
0
0
0
% S
% Thr:
8
0
0
0
0
0
0
0
8
62
77
0
0
8
0
% T
% Val:
0
31
0
0
0
0
0
0
0
0
0
0
24
70
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _